Für den Inhalt der Angaben zeichnet die Projektleitung verantwortlich.
Dieses von der Gebert Rüf Stiftung geförderte Projekt wird von folgenden weiteren Projektpartnern mitgetragen: Laboratory of Biomechanical Orthopedics (LBO), EPFL; Division of Maxillofacial Surgery, University Hospital CHUV; Musculoskeletal Research Unit, University of Zürich; CTI
Förderbeitrag: CHF 381'000
Dauer: 09.2016 - 09.2018
Handlungsfeld: Pilotprojekte, 1998 - 2018
Dr. Ulrike Kettenberger
Ecole Polytechnique Fédérale de Lausanne
Laboratory of Biomechanical Orthopedics
1015 Lausanne (Schweiz)
- ulrike.kettenberger@epfl. ch
Bone defects can occur at almost any part of the human skeleton and can be caused by trauma or diseases such as cysts or bone tumors. In case those defects exceed a critical size or are located at sensitive sites, the human body is not able to repair them itself and a surgical intervention becomes necessary. The standard treatment is filling the defect with either autologous bone, that is taken from another site of the patient’s body, or with commercially available bone substitutes. Those bone substitutes can be either synthetic or produced from natural sources such as cadaveric or animal bone. One inherent disadvantage of currently available bone substitutes is their bulky nature so that their application requires a large bone opening.
FLOWBONE is the first all in one therapy specifically adapted for the minimal invasive treatment of non load bearing, difficult to access bone defects. It can equally be used to reinforce weak bone structures. FLOWBONE comes as a ready to use material in a syringe that can be applied to the human skeleton through small natural or artificial orifices. The very simple application technique of FLOWBONE makes it usable for a wide range of potential customers in many medical disciplines such as orthopedics, traumatology, reconstructive medicine or dentistry.
Was ist das Besondere an diesem Projekt?
The FLOWBONE material is a joint development between clinicians and scientists. It is highly innovative as it follows completely new approach to repair bone defects in the human body. Instead of just filling the defect with material, FLOWBONE initiates the body’s own repair processes. Beside the positive biological effects, the material can also convince with its simple application technique and is therefore highly attractive for clinicians from many disciplines.
At present, the FLOWBONE project is still a research project and located in the Laboratory of Biomechanical Orthopedics (LBO) on the EPFL campus. A first proof of concept for the efficacy of FLOWBONE has been achieved in vivo in rodents, the final evaluation of the material in a large animal model is scheduled for 2017.
No publications directly linked to the project
Am Projekt beteiligte Personen
Letzte Aktualisierung dieser Projektdarstellung 17.10.2018