Für den Inhalt der Angaben zeichnet die Projektleitung verantwortlich.
Dieses von der Gebert Rüf Stiftung geförderte Projekt wird von folgenden weiteren Projektpartnern mitgetragen: Optics & Photonics Technology laboratory, Ecole Polytechnique Fédérale de Lausanne.
Förderbeitrag: CHF 309'000
Dauer: 03.2017 - 08.2018
Handlungsfeld: Pilotprojekte, 1998 - 2018
Dr. Nicolas Descharmes
Ecole Polytechnique Fédérale de Lausanne
Optics & Photonics Technology Laboratory
Rue de la Maladière 71b
2002 Neuchâtel (Schweiz)
- nicolas.descharmes@epfl. ch
The capacity to measure low abundance molecules is a common target in several research areas. With this goal in mind, we develop, in this project, a novel multipurpose microscopy tool capable of greatly improving the sensitivity of many routine and well-established analytical techniques. Not only the envisioned product will find interest in the research community, it also has the potential to shake up the sectors of life sciences and medical analyses. Such improved performances are achieved through the use of specific, precisely structured, microscopy slides. These engineered substrates can be used directly with the current, commercially available systems. For ultimate performances, however, the use of a dedicated illumination system is required. This system will also be developed in the course of this project.
Was ist das Besondere an diesem Projekt?
When trying to improve the sensitivity of a detection method, most of the efforts are usually engaged in the improvement of the analytical instruments themselves (e.g. more powerful light source, higher sensitivity cameras, better microscope objectives, etc.). On the contrary, very little energy is typically placed in the development of the substrates onto which the sample is deposited. This is where our technology comes into action. Placing the substrates at the heart of the improvement strategy is in this sense disruptive. We believe we can gain at least one order of magnitude in sensitivity by precisely engineering the substrates used for the analyses.
The project started on Jan 1, 2017 and is currently ongoing. At this stage, we have successfully assembled our test bench and demonstrated the concept of 5 new types of substrates. We also have taken steps towards the patenting of our technology. While two groups have already agreed to test our substrates, we are actively looking for more partners to take part to the testing.
None so far
None so far
Am Projekt beteiligte Personen
Letzte Aktualisierung dieser Projektdarstellung 17.10.2018