Projektdarstellungen auf der Webseite

Jedes von der Gebert Rüf Stiftung geförderte Projekt wird mit einer Webdarstellung zugänglich gemacht, die über die Kerndaten des Projektes informiert. Mit dieser öffentlichen Darstellung publiziert die Stiftung die erzielten Förderresultate und leistet einen Beitrag zur Kommunikation von Wissenschaft in die Gesellschaft.


condenZero – Opening new Frontiers in Cryo Electron Microscopy


Für den Inhalt der Angaben zeichnet die Projektleitung verantwortlich.


Dieses von der Gebert Rüf Stiftung geförderte Projekt wird von folgenden weiteren Projektpartnern mitgetragen:


  • Projekt-Nr: GRS-072/21 
  • Förderbeitrag: CHF 150'000 
  • Bewilligung: 28.10.2021 
  • Dauer: 01.2022 - 04.2023 
  • Handlungsfeld:  InnoBooster, seit 2018



Many modern science disciplines require cold temperatures close to the «absolute zero point» at -273°C, for applications such as superconductivity (e.g., used in medical scanning devices) or quantum computing. In cryo- TEM (transmission electron microscopy), a Nobel-prize winning research tool to study molecules/proteins (drug development) and materials, these temperatures can only be sustained within ca. 15 minutes. With this re- striction, scientists in low temperature cryo-TEM are slowed down in creating high-throughput scientific results. Our spin-off company, condenZero, invented a cooling technology to enable cryo-experiments to last 24 hours instead of 15 minutes.
Currently, condenZero builds an experimental system where the cryo-sample holder is combined with a sec- ondary product that shapes magnetic fields around the sample. Both products are crucial to enable the study of new materials with exotic magnetic properties, such as “skyrmions” – a quantum entity in atomic physics that promise data storage at much higher densities than ever before. Another research field is the study of magnetic nanoparticles for localized drug-delivery in the human body.


To operate both devices in this project, the electron microscope had to be modified. Such modifications are not feasible for almost all other users, making this solution unsuitable for widespread commercialization. With In- noBooster, we will be able to build an interim product that will be able to combine both strength of our devices into a single product: Revolutionary cooling capabilities and shaping magnetic fields in a cryo-TEM experiment. This will allow us to reach customers in research fields at the intersection of materials and life sciences without the necessity of modifying the microscope. In the first half of the GRS project, we finalized the 3D-models and fabricated key components as proof-of-concept studies. By end of 2022, we produced a first prototype cooling sample holder with 24 electrical contacts to power electromagnets in the sample space. Further R&D efforts are deployed in miniaturizing the magnetic coils.
For future prototype development and improving technical performance, condenZero just recently filed an Innosuisse project together with the EMPA and inspire AG. In 2023 new tests are planned with prototype pre-sales.


Am Projekt beteiligte Personen

Letzte Aktualisierung dieser Projektdarstellung  18.03.2024